Location in the nucleus foretells chromosome anomalies
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Loading... - Lara Vossen
- 18 Jul 2022
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Normal human cells have two copies of each chromosome. By contrast, many cancer cells have abnormal numbers of chromosomes, either having extra copies or lacking some. The most common reason for such abnormalities is the result of defective cell division, specifically, a failure to distribute the cell’s chromosomes equally between the two newly forming daughter cells. The 3D location of chromosomes in the nucleus before cell division affects their likelihood of being incorrectly partitioned in the daughter cells.
Regular human cells have two copies of every chromosome. Against this, many most cancers cells have irregular numbers of chromosomes, both having additional copies or missing some. The most typical purpose for such abnormalities is the results of faulty cell division, particularly, a failure to distribute the cell's chromosomes equally between the 2 newly forming daughter cells.
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